Jason M. Newbern

This study examines sex-dependent changes in circulating steroid hormones and cortical gene expression following traumatic brain injury in mice, revealing sex-specific alterations in hormone levels and gene expression related to immune and tissue responses.

This paper develops a vaccine formulation to reduce inflammation after traumatic brain injury by inducing immunosuppressive cells and improving motor function in mice.

This study shows that hyperactivation of MEK1 in cortical glutamatergic neurons leads to axon outgrowth deficits and impaired motor learning, but not locomotor activity.

The paper investigates how distinct hyperactive RAS/MAPK alleles affect cortical GABAergic interneurons, revealing shared molecular programs and a role for increased neural activity in altering interneuron subtypes.

This study investigates the role of ERK1/2 signaling in the development of MGE-derived glia and cortical inhibitory neurons, showing its necessity for glial number and activity-dependent responses in neurons.

This study shows that cholinergic interneurons in the nucleus accumbens core mediate cue-induced nicotine seeking and associated glutamatergic plasticity through specific receptor mechanisms.

The paper analyzes dystrophin-deficient muscle transcriptomes in C. elegans to identify signaling pathway changes during Duchenne muscular dystrophy progression and develops a screening method for genetic partners of dystrophin.