Genetic & Genomic MedicinemedRxivPreprint
Dynamic interplay of polygenic risk across brain disorders, neuropathological endophenotypes, and neuropsychiatric symptoms
Nienke Mekkes, Umesh Kumar, Eric Hoekstra…·Inge R. Holtman
The paper integrates genotype, clinical, and neuropathological data from 2,553 donors to show genetic risk overlaps across brain disorders and neuropsychiatric symptoms.
DOI 10.64898/2026.06.30.26356924