Author

Lisa A. Reynolds

University of VictoriaORCID 0000-0002-2969-2296Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Rachael D. FitzPatrickiD· 2 shared Aleksandra M. Przydatek· 1 shared Ana Paula Cota· 1 shared Andrew N. Robinson· 1 shared Brandon E. MoelleriD· 1 shared Craig E. BrowniD· 1 shared Dominique M. GattiiD· 1 shared Jakob KörbeliniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Rachael D. FitzPatrickORCID

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2 papers

Recent·Most cited

Dynamic fates of dietary antigen-specific T helper cells in a model of early life oral tolerance

Rachael D. FitzPatrick, Aleksandra M. Przydatek, Dominique M. Gatti, Natasha J. Norton, Jenna M. Lane, Brandon E. Moeller, Andrew N. Robinson, Lisa A. Reynolds

This study investigates the fate of CD4+ T cells during early life oral tolerance development in mice, finding that OVA-specific Tregs and Th2 cells emerge, while Th2 cells are suppressed upon systemic challenge.

bioRxiv · Aug 30, 2025 · PreprintImmunology

A pathogenic role for IL-10 signalling in capillary stalling and cognitive impairment in type 1 diabetes

Sorabh Sharma, Manjinder S. Cheema, Patrick L. Reeson, Kamal Narayana, Roobina Boghozian, Ana Paula Cota, Tara P. Brosschot, Rachael D. FitzPatrick, Jakob Körbelin, Lisa A. Reynolds, Craig E. Brown

This study shows IL-10 signalling contributes to capillary stalling and cognitive impairment in type 1 diabetes by increasing vascular obstructions and reducing blood flow.

Nature Metabolism · Nov 4, 2024Peer-reviewedNeuroscience