Michael A. Koldobskiy

This study shows that combining decitabine and entinostat increases immunogenicity of low-mutation sarcomas by upregulating antigens and enhancing T cell responses.

The paper analyzes DNA methylation stochasticity in AML subtypes, identifying high-entropy subtypes and linking methylation entropy to transcriptional variability and leukemogenesis.

This study shows DNMT3AR882H mutations are not required for maintaining AML but are linked to higher leukemia stem cell frequency.

This study identifies convergence of aging and rejuvenation-related DNA methylation changes on PRC2 target genes in reprogrammed mouse skin.

The paper analyzes DNA methylation entropy in human and mouse datasets, finding associations with sequence features, developmental patterns, and gene expression variability.

This paper shows that reprogramming diabetic fibroblasts into naive hiPSC using tankyrase inhibitors improves vascular progenitor generation and revascularization in ischemic retinas.