Author

Daiki Karigane

Japan Society for the Promotion of ScienceORCID 0000-0002-4017-5193Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Amy C. FaniD· 3 shared Ravindra MajetiiD· 3 shared Thomas KöhnkeiD· 3 shared Yusuke NakauchiiD· 3 shared Aaron M. NewmaniD· 2 shared Andrew J. GentlesiD· 2 shared Asiri EdiriwickremaiD· 2 shared Miles Hamilton LindeiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersCancer Biology

Amy C. FanORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 13, 2026

Single cell multi-omics enables high-resolution identification and functionalpurification of human acute myeloid leukemia stem cells

Asiri Ediriwickrema, Yusuke Nakauchi, Thomas Köhnke…·Ravindra Majeti

The paper identifies and isolates human AML leukemia stem cells using single-cell multi-omics and establishes a prognostic gene signature for clinical relevance.

DOI 10.64898/2026.07.12.737989

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologyCancer DiscoveryPeer-reviewedNov 20, 2025

DNMT3AR882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency

Thomas Köhnke, Daiki Karigane, Eleanor Hilgart…·Ravindra Majeti

This study shows DNMT3AR882H mutations are not required for maintaining AML but are linked to higher leukemia stem cell frequency.

5 citations

humanDNA methylation

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Cancer BiologyCell ReportsPeer-reviewedSep 1, 2025

A single cell framework identifies functionally and molecularly distinct multipotent progenitors in adult human hematopoiesis

Asiri Ediriwickrema, Yusuke Nakauchi, Amy C. Fan…·Ravindra Majeti

This study identifies new functionally and molecularly distinct multipotent progenitors in adult human hematopoiesis using multiomic single cell analyses and functional assays.

10 citationstop 2%

humanscRNA-seq

𝕏 PostBluesky