Author

Vivien W. Ho

European Bioinformatics InstituteORCID 0000-0002-2992-0252Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander V. PredeusiD· 1 shared Anna O'Carroll· 1 shared Annalisa BunielloiD· 1 shared Carrie M. SpratfordiD· 1 shared Clément ChatelainiD· 1 shared Daniel ConsidineiD· 1 shared Daniel SeatoniD· 1 shared Dániel SüvegesiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Alexander V. PredeusORCID

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2 papers

Recent·Most cited

The Human Pleiotropic Map of GWAS Associations and Therapeutic Implications

Yakov A. Tsepilov, Dániel Süveges, Daniel Considine, Szymon Szyszkowski, Xiangyu Jack Ge, Irene López Santiago, Polina V. Rusina, Tobi Alegbe, Vivien W. Ho, Kirill Tsukanov, Juan María Roldán‐Romero, Ines A. Smit, Helena Cornu, Laura Wiseman Harris, Kaur Alasoo, , David Ochoa

This paper analyzes 100,526 GWAS to identify pleiotropic genes and their therapeutic implications, finding that highly pleiotropic genes are associated with safety liabilities and that combining PAV support with intermediate pleiotropy improves therapeutic success.

bioRxiv · May 1, 2026 · PreprintGenomics

Intermediate Progenitor cells provide a transition between hematopoietic progenitors and their differentiated descendants

Carrie M. Spratford, Lauren M. Goins, Fangtao Chi, Juliet R. Girard, Savannah N. Macias, Vivien W. Ho, Utpal K. Banerjee

The paper identifies intermediate progenitor cells in Drosophila using a split-GAL4 construct and shows they regulate cell fate through Notch signaling and the Ras pathway.

Development · Dec 15, 2021Peer-reviewedDevelopmental Biology