Author

Zhongan Yang

University of California, Los AngelesORCID 0000-0002-2996-1708Unclaimed ORCID profile · follow to get notified of new preprints

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Zhongan Yang1 paper

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Approach:statistical model· 1

Frequent Co-Authors

Abdulsamie M. PateliD· 1 shared Alexandria EvansiD· 1 shared Daniel H. GeschwindiD· 1 shared Giovanni CoppolaiD· 1 shared Jessica E. DavisiD· 1 shared Kevin J. WojtaiD· 1 shared Lianne Maria ReusiD· 1 shared Marco P. BoksiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Abdulsamie M. PatelORCID

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2 papers

Recent·Most cited

Accurate DNA Methylation Predictor for C9orf72 Repeat Expansion Alleles in the Pathogenic Range

Naren Ramesh, Alexandria Evans, Kevin J. Wojta, Zhongan Yang, Marco P. Boks, René S. Kahn, Sterre C.M. de Boer, Sven J. van der Lee, Yolande A.L. Pijnenburg, Lianne Maria Reus, Roel A. Ophoff

The paper develops a DNA methylation predictor for C9orf72 repeat expansion carriers using EPICv2 data, achieving 98.6% accuracy and identifying four carriers in an independent cohort.

Human Genetics and Genomics Advances · Oct 1, 2025Peer-reviewedGenetics

Functional regulatory variants implicate distinct transcriptional networks in dementia

Yonatan A. Cooper, Noam Teyssier, Nina M. Dräger, Qiuyu Guo, Jessica E. Davis, Sydney M. Sattler, Zhongan Yang, Abdulsamie M. Patel, Sarah J. Wu, Sriram Kosuri, Giovanni Coppola, Martin Kampmann, Daniel H. Geschwind

The paper identifies functional regulatory variants in GWAS loci for dementia, revealing cell-type specific transcriptional networks involved in disease risk.

Science · Aug 18, 2022Peer-reviewedGenetics