Lianne Maria Reus

The paper develops a DNA methylation predictor for C9orf72 repeat expansion carriers using EPICv2 data, achieving 98.6% accuracy and identifying four carriers in an independent cohort.

This study maps quantitative trait loci for CSF metabolites and identifies associations with brain traits, revealing potential neurobiological pathways.

The paper identifies 11 novel genetic loci associated with Alzheimer's disease and hippocampal volume using cross-trait analysis and functional annotation.

This study uses gene expression imputation to identify candidate genes and tissue-specific associations linked to frontotemporal dementia risk loci.

This study examines associations between vascular risk factors and brain MRI indices in UK Biobank, finding that higher vascular risk is linked to poorer brain health across macro- and microstructural measures.

Across 5,216 UK Biobank adults, males had larger brain volumes and surface areas, females thicker cortices and stronger default-mode connectivity; male variance was generally greater.

This study finds reduced white matter integrity in individuals with major depressive disorder using UK Biobank imaging data, but no significant subcortical volume differences.

This study examines the genetic overlap between major psychiatric disorders and brain structure in UK Biobank data but finds no significant associations.