Aging trajectories of memory CD8+ T cells differ by their antigen specificity
Ines Sturmlechner, Abhinav K. Jain, Bin Hu, Rohit R. Jadhav, Wenqiang Cao, Hirohisa Okuyama, Lü Tian, Cornelia M. Weyand, Jörg J. Goronzy
The paper examines how aging affects antigen-specific memory CD8+ T cells in EBV infection, finding distinct aging trajectories with changes in gene expression and TCR diversity.
Nature Communications · Jul 10, 2025Peer-reviewedImmunology