Wei Lü

The paper shows that temperature and Ca2+ alter TRPM4's pharmacology, revealing how these factors influence ligand binding and channel function.

The paper identifies and classifies ion channels across species, revealing functional insights into understudied CALHM channels through sequence, structure, and functional data integration.

This study identifies SLITRK3 mutations in humans linked to epileptic encephalopathy and shows their loss-of-function effect in neurons and mice, highlighting a role in synapse development and neurological function.