Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis
Gitali Naim, Hadar Romano-Zadaka, Sivan Amidror, David Jessula Levy, Adva Cohen, Carmel Sochen, Hadar Gilberg, Nairouz Farah, Vladislav Rudenko, Yasmin Yarden‐Rabinowitz, Mengyang Feng, Rotem Tsentsarevsky, Ziv Brodie, Yasmin Reich, Ariel Simon, , Nissan Yissachar
The paper develops an optogenetics-integrated gut organ culture system to study enteric neuron dynamics and their impact on gut homeostasis, revealing distinct neuronal roles in immune and barrier functions.
Nature Communications · Nov 14, 2025Peer-reviewedNeuroscience