A single DPE core promoter motif contributes to in vivo transcriptional regulation and affects cardiac function
Anna Sloutskin, Dekel Itzhak, Georg Vogler, Diana Ideses, Hadar Alter, Hadar Shachar, Tirza Doniger, Manfred Frasch, Rolf Bodmer, Sascha H. C. Duttke, Tamar Juven‐Gershon
The paper shows that a single DPE core promoter motif mutation in Drosophila affects cardiac function by disrupting Tinman's regulatory network.
bioRxiv · Jun 11, 2023 · PreprintDevelopmental Biology