Author

Vladislav Rudenko

Weizmann Institute of Science

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:database / resource· 1

Frequent Co-Authors

Moshe BitoniD· 3 shared Avital Sarusi-PortugueziD· 2 shared Aviya Habshush MenachemiD· 2 shared Barak Toval· 2 shared Carmel SocheniD· 2 shared Nissan YissachariD· 2 shared Sacha LeboniD· 2 shared V. V. Holiar· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersImmunology

Moshe BitonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

IL-13 Induces a Tuft Cell-Intrinsic CD45 Checkpoint to Limit Intestinal Type 2 Immunity

Carmel Sochen, Sacha Lebon, Aviya Habshush Menachem, Avital Sarusi-Portuguez, V. V. Holiar, Vladislav Rudenko, Barak Toval, Jingjing Liu, Yishai Levin, Ella Vaaknin, Noa Rosenthal, Noa Tiferet, Irit Orr, Shifra Ben‐Dor, Rebecca Haffner‐Krausz, , Moshe Biton

This study identifies CD45 as a tuft cell-intrinsic checkpoint that limits intestinal type 2 immunity through an IL-13-induced negative feedback mechanism.

bioRxiv · Jul 26, 2026 · PreprintImmunology

Epithelial MHC II antigen presentation dynamically informs intestinal homeostasis and injury

V. V. Holiar, Vladislav Rudenko, Chen Weller, Mariia Naumova, Sacha Lebon, Marco Canella, Petro Busko, Avital Sarusi-Portuguez, Tali Shalit, Aviya Habshush Menachem, Idan Adir, Zachary Petrover, Polina Greenberg, Corine Katina, Polina Gradchenko, , Moshe Biton

This study shows that epithelial MHC II antigen presentation encodes tissue state and injury signals, maintaining homeostasis and promoting tolerance, while shifting toward damage-associated antigens during inflammation.

bioRxiv · Mar 20, 2026 · PreprintImmunology

Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis

Gitali Naim, Hadar Romano-Zadaka, Sivan Amidror, David Jessula Levy, Adva Cohen, Carmel Sochen, Hadar Gilberg, Nairouz Farah, Vladislav Rudenko, Yasmin Yarden‐Rabinowitz, Mengyang Feng, Rotem Tsentsarevsky, Ziv Brodie, Yasmin Reich, Ariel Simon, , Nissan Yissachar

The paper develops an optogenetics-integrated gut organ culture system to study enteric neuron dynamics and their impact on gut homeostasis, revealing distinct neuronal roles in immune and barrier functions.

Nature Communications · Nov 14, 2025Peer-reviewedNeuroscience

WHIX is a T6SS secretion domain found in polymorphic double-edged sword effectors

Chaya Mushka Fridman, Kinga Keppel, Vladislav Rudenko, Jon Altuna-Alvarez, David Albesa-Jové, Eran Bosis, Dor Salomon

The paper identifies WHIX as a T6SS secretion domain that enables the delivery of effectors with one or two toxic domains, requiring specific immunity proteins to counteract their toxicity.

PLoS Biology · Mar 17, 2025Peer-reviewedMicrobiology