Aleks Ponjavic

Single-molecule flow cytometry

This paper introduces single-molecule flow cytometry (smFC) to detect low-abundance membrane proteins with digital precision, revealing previously undetectable distributions in cancer cells.

HP1β and densely packed chromatin form separate microdomains in mouse ES cells, which are reconfigured upon exit from naive pluripotency

Active Remote Focus Stabilization in Oblique Plane Microscopy

This paper introduces a method for stabilizing the light-sheet in oblique plane microscopy without using sample fluorescence, achieving high axial precision for long-term imaging.

Redistribution of proteasomes through diffusion and cytoskeleton-dependent mechanisms upon stress induced by protein aggregates

The paper quantifies proteasome re-organization during proteotoxic stress using single-molecule microscopy and shows cytoskeleton-dependent movement restrictions.

4D imaging reveals stage dependent random and directed cell motion during somite morphogenesis

The paper uses live imaging to study cell movement during somite formation in chick embryos, revealing both random and directed motion in different regions.