Author

Patricio Pichling

National Institutes of HealthORCID 0000-0002-3051-9458Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian R. Ferré-D’AmaréiD· 1 shared Ashish LaliD· 1 shared Christopher P. JonesiD· 1 shared Christopher R. FullenkampiD· 1 shared Erica C. PehrssoniD· 1 shared Ioannis GrammatikakisiD· 1 shared John S. SchneeklothiD· 1 shared Logan Tenney· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Adrian R. Ferré-D’AmaréORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 28, 2025

HNRNPH1-mediated splicing events regulate EIF4G1 transcript variant composition and the organization of the AURKA 5' UTR

Tayvia Brownmiller, Soumya Sundara Rajan, Tamara L. Jones…·Natasha J. Caplen

This study identifies HNRNPH1-regulated splicing events affecting EIF4G1 transcript variants and AURKA 5' UTR structure, influencing protein expression and function.

DOI 10.1101/2025.07.28.667222

humanbulk RNA-seq

BiochemistryAngewandte Chemie International EditionPeer-reviewedMay 1, 2025

Machine learning-augmented molecular dynamics simulations (MD) reveal insights into the disconnect between affinity and activation of ZTPriboswitch ligands

Christopher R. Fullenkamp, Shams Mehdi, Christopher P. Jones…·John S. Schneekloth

The paper uses machine learning-augmented MD simulations to study ZTP riboswitch ligand interactions, finding that ligand on-rates, not binding affinity, determine activation potency.

13 citations

bacteria (other)structural biology