Tayvia Brownmiller

This study shows that EWSR1 forms a ribonucleoprotein network with nascent RNA, and its loss leads to compensatory reorganization of FUS and TAF15, revealing functional redundancy in maintaining nascent RNA homeostasis.

The paper identifies U2AF2's role in intron retention of lncRNAs PURPL and MALAT1, showing how this process affects their localization and promotes cell proliferation and migration.

This study identifies HNRNPH1-regulated splicing events affecting EIF4G1 transcript variants and AURKA 5' UTR structure, influencing protein expression and function.

This study identifies ETS1 as a target of the EWSR1::FLI1 fusion oncoprotein in Ewing sarcoma, showing it regulates TNS3 expression, which promotes cell movement and is linked to metastasis.

The paper shows HNRNPH1 destabilizes G-quadruplexes in G-rich RNA sequences, affecting alternative splicing of an oncogenic fusion transcript in Ewing sarcomas.