Natasha J. Caplen

This study shows that combining oncolytic viruses with antibodies enhances immune-mediated killing of osteosarcoma by overcoming immunosuppression.

This study shows that EWSR1 forms a ribonucleoprotein network with nascent RNA, and its loss leads to compensatory reorganization of FUS and TAF15, revealing functional redundancy in maintaining nascent RNA homeostasis.

The paper identifies U2AF2's role in intron retention of lncRNAs PURPL and MALAT1, showing how this process affects their localization and promotes cell proliferation and migration.

This study shows that the oncolytic Maraba virus MG1 can directly kill Ewing sarcoma cells and enhance NK cell-mediated cytotoxicity against them.

This study identifies HNRNPH1-regulated splicing events affecting EIF4G1 transcript variants and AURKA 5' UTR structure, influencing protein expression and function.

The paper shows HNRNPH1 destabilizes G-quadruplexes in G-rich RNA sequences, affecting alternative splicing of an oncogenic fusion transcript in Ewing sarcomas.