Ioannis Grammatikakis

This study shows that Sigma-1 receptor promotes glycolysis in neuronal systems by suppressing GRIM19, affecting NAD+/NADH metabolism and mitochondrial activity.

The paper identifies U2AF2's role in intron retention of lncRNAs PURPL and MALAT1, showing how this process affects their localization and promotes cell proliferation and migration.

This study shows TAp73 regulates lipid metabolism in lung tumor microenvironment to enhance anti-tumor immunity through T-cell activation.

This study identifies HNRNPH1-regulated splicing events affecting EIF4G1 transcript variants and AURKA 5' UTR structure, influencing protein expression and function.

This study identifies ZMAT3 as a regulator of HKDC1 transcription through JUN, suppressing mitochondrial respiration in colorectal cancer cells.

This study identifies Matrin3's role in regulating CDC14B alternative splicing, which affects cell proliferation and mitotic spindle dynamics in colorectal cancer cells.

The paper shows HNRNPH1 destabilizes G-quadruplexes in G-rich RNA sequences, affecting alternative splicing of an oncogenic fusion transcript in Ewing sarcomas.