Tapan K. Nayak

This study investigates allosteric signal communication in AChRs, showing distinct activation pathways in liganded vs unliganded states and identifying a continuous allosteric network.

The paper investigates TRPML3's role in autophagy-induced gene expression changes in neuronal cells and suggests it may serve as a genetic marker for neurodegenerative disorders.

This study investigates agonist binding to the unliganded open state of neuromuscular acetylcholine receptors using single-channel recordings, molecular dynamics, and mutagenesis, revealing the role of surface charges in enhancing binding affinity.