BiophysicsbioRxivPreprint
Role of surface negative charges in agonist binding to the unliganded open state of the neuromuscular acetylcholine receptor
Nadira Khatoon, Tapan K. Nayak
This study investigates agonist binding to the unliganded open state of neuromuscular acetylcholine receptors using single-channel recordings, molecular dynamics, and mutagenesis, revealing the role of surface charges in enhancing binding affinity.
DOI 10.1101/2024.12.23.630096