Author

Nicolas Dupont

Hôpital Necker-Enfants MaladesORCID 0000-0002-3056-9906Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Franck OuryiD· 2 shared A. Madelaine· 1 shared Aleksandra Nadaj‐PaklezaiD· 1 shared Alexandre BénaniiD· 1 shared Anaïs Chanut· 1 shared Anne‐Sophie ArmandiD· 1 shared Apolline ImbardiD· 1 shared Arnaud Hubas· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Franck OuryORCID

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2 papers

Recent·Most cited

Parathyroid Hormone Receptor 1 Signaling Encodes Multifaceted Metabolic Programs in AgRP Neurons

Mathieu Galerne, Eleni Siopi, Audrey Rousseaud, Lea Vinel, Nour Nesto, François Mailliet, Fabienne Liénard, Valérie Boitez, Emmanuelle Nédélec, Stéphanie Moriceau, Manon Rivagorda, Maya Faour, Julien Castel, Soham Saha, Christiane Schreiweiss, , Franck Oury

This study identifies PTH1R signaling in AgRP neurons as a mechanism controlling feeding behavior and nutrient partitioning through distinct kinase activation and lipophagic processes.

bioRxiv · Oct 15, 2026 · PreprintNeuroscience

Novel variants in ryanodine receptor type 3 predispose to acute rhabdomyolysis due to impaired autophagy

Hortense de Calbiac, Laure Caccavelli, Solène Renault, Marine Madrange, Quentin Raas, Marjolène Straube, Guy Brochier, Emmanuelle Lacène, Anaïs Chanut, A. Madelaine, Clémence Labasse, Lylia Mekzine, Sebastián Montealegre, Nicolas Goudin, Aleksandra Nadaj‐Pakleza, , Pascale de Lonlay

This study identifies rare RYR3 variants causing recurrent rhabdomyolysis by impairing autophagy and mitochondrial function, highlighting RyR3's role in muscle stress adaptation.

medRxiv · Mar 3, 2026 · PreprintGenetic & Genomic Medicine