Author

Misha Fini

University of North Carolina at Chapel HillORCID 0000-0002-3063-6064Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Benjamin Garrett VincentiD· 2 shared Dhuvarakesh KarthikeyaniD· 2 shared Jin Seok LeeiD· 2 shared Alex M. JaegeriD· 1 shared Alex RubinsteyniD· 1 shared Emily PauliD· 1 shared Jason A. Garness· 1 shared Jessica Alley· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Benjamin Garrett VincentORCID

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2 papers

Recent·Most cited

Immunodominance Hierarchy of Endogenous BBN963 Bladder Cancer Antigens Remains Stable Under Anti-PD1 and Anti-CTLA4 Immunotherapy

Misha Fini, Jessica Alley, Steven P. Vensko II, Dhuvarakesh Karthikeyan, Jin Seok Lee, Jason A. Garness, Emily Paul, Alex M. Jaeger, Nilu P Goonetilleke, William Y. Kim, Benjamin Garrett Vincent

This study identifies a stable immunodominance hierarchy of tumor antigens in a murine bladder cancer model under anti-PD1 and anti-CTLA4 therapy, suggesting broad antigen selection could improve immunotherapy.

bioRxiv · May 27, 2026 · PreprintCancer Biology

ACE Configurator for ELISpot (ACE): Optimizing Combinatorial Design of Pooled ELISpot Assays with an Epitope Similarity Model

Jin Seok Lee, Dhuvarakesh Karthikeyan, Misha Fini, Benjamin Garrett Vincent, Alex Rubinsteyn

ACE optimizes ELISpot assay design by using an epitope similarity model to reduce false positives and improve efficiency.

Briefings in Bioinformatics · Nov 22, 2023Peer-reviewedBioinformatics