Bola-amphiphilic dendrimer empowers imatinib to target metastatic ovarian cancer stem cells via beta-catenin-HRP2 signaling axis
Zeyu Shi, Margarita Artemenko, Weiyu Yu, Ming Zhang, Canhui Yi, Peng Chen, Shuting Lin, Zhancun Bian, Baoping Lian, Fanzhen Meng, Jiaxuan Chen, Tom Roussel, Ying Li, Karen K. L. Chan, Philip P.C. Ip, , Alice S.T. Wong
This study develops a nanoformulation Bola/IM to target metastatic ovarian cancer stem cells via the beta-catenin-HRP2 signaling axis, showing improved efficacy and synergy with cisplatin.
ACS Applied Materials & Interfaces · Jan 3, 2025Peer-reviewedCancer Biology