Author

Vanaporn Wuthiekanun

Mahidol UniversityORCID 0000-0002-3074-0742Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Direk LimmathurotsakuliD· 2 shared Apichai TuanyokiD· 1 shared Ayalew MergiaiD· 1 shared Chalita ChomkatekaewiD· 1 shared Charles A. YowelliD· 1 shared Chie NakajimaiD· 1 shared Claire ChewapreechaiD· 1 shared Elizabeth M. BattyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersEvolutionary Biology

Direk LimmathurotsakulORCID

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2 papers

Recent·Most cited

A 28-year evolution experiment on Burkholderia pseudomallei survival in nutrient-depleted sterile water

Chalita Chomkatekaew, Premjit Amornchai, Sayan Langlah, Janjira Thaipadungpanit, Elizabeth M. Batty, Direk Limmathurotsakul, Kalayanee Chairat, Kanyarat Sueksakrit, Siribha Apinan, Phornpimon Tipthara, Joel Tärning, Víctor Rodríguez-Bouza, John A. Lees, Jukka Corander, Nicholas Day, , Claire Chewapreecha

This study tracks the 28-year evolution of a Burkholderia pseudomallei strain in sterile water, identifying genetic changes and metabolic adaptations to nutrient-depletion.

bioRxiv · Feb 6, 2026 · PreprintEvolutionary Biology

Genomic Insights into Ceftazidime Resistance in Burkholderia pseudomallei: Discovery of A172T Mutation, and Palindromic GC-Rich Repeat Sequences Facilitating penA Duplication and Amplification.

Apichai Tuanyok, Chie Nakajima, Tiernan Noll, Md. Siddiqur Rahman Khan, Pacharapong Khrongsee, Charles A. Yowell, Yu-Ping Xiao, Vanaporn Wuthiekanun, Narisara Chantratita, Henry S. Heine, Kuttichantran Subramaniam, Yasuhiko Suzuki, Direk Limmathurotsakul, Ayalew Mergia

This study identifies a novel A172T mutation and penA gene duplication driven by PGCRRS as key factors in ceftazidime resistance in Burkholderia pseudomallei.

Antimicrobial Agents and Chemotherapy · Jul 21, 2025Peer-reviewedMicrobiology