Integrating bacterial genomics and host transcriptomics links Burkholderia pseudomallei variation to melioidosis mortality and neutrophil responses
Arin Wongprommoon, Phumrapee Boonklang, Katie L Burnham…·Claire Chewapreecha
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Mahidol UniversityORCID 0000-0003-3906-7379Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Arin Wongprommoon, Phumrapee Boonklang, Katie L Burnham…·Claire Chewapreecha
Charlene Mae Salao Cagape, Théo Dokhelar, Natnaree Saiprom…·Vanina Guernier
This study compares culture and molecular detection methods for B. pseudomallei in Thai soil samples, finding that qPCR with ACER enrichment detects more positives than culture alone.
Éilís C. Bragginton, Charlotte K. Colenso, Michael Beer…·JAMES M. SPENCER
This paper characterizes OXA-57, a class D β-lactamase from Burkholderia pseudomallei, showing its activity against penicillins and cephalosporins, limited carbapenem hydrolysis, and structural insights into its mechanism.
Apichai Tuanyok, Chie Nakajima, Tiernan Noll…·Ayalew Mergia
This study identifies a novel A172T mutation and penA gene duplication driven by PGCRRS as key factors in ceftazidime resistance in Burkholderia pseudomallei.
Narisara Chantratita, Khine Khine Su, Chanwit Tribuddharat, Nay Myo Aung
The paper compares ERIC-PCR and MLST for typing Burkholderia pseudomallei isolates, finding ERIC-PCR to be more discriminatory and cost-effective for resource-limited settings.