Distinct glycosaminoglycan chain length and sulfation patterns required for cellular uptake of Tau, Aβ, and α-Synuclein
Barbara Elena Stopschinski, Brandon B. Holmes, Gregory M. Miller, Victor A. Manon, Jaime Vaquer‐Alicea, William L. Prueitt, Linda C. Hsieh‐Wilson, Marc I. Diamond
The paper identifies specific glycosaminoglycan (GAG) structural requirements for the uptake of Tau, Aβ, and α-synuclein aggregates by cells.
Journal of Biological Chemistry · May 11, 2018Peer-reviewedNeuroscience