Author

Linda C. Hsieh‐Wilson

California Institute of TechnologyORCID 0000-0001-5661-1714Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Gregory M. Miller· 2 shared Alexander W. SorumiD· 1 shared Barbara Elena StopschinskiiD· 1 shared Brandon B. HolmesiD· 1 shared Jaime Vaquer‐AliceaiD· 1 shared Jennifer N. RauchiD· 1 shared John Jing-Wei CheniD· 1 shared Kenneth S. KosikiD· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Gregory M. Miller

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2 papers

Recent·Most cited

NeuroscienceJournal of Biological ChemistryPeer-reviewedMay 11, 2018

Distinct glycosaminoglycan chain length and sulfation patterns required for cellular uptake of Tau, Aβ, and α-Synuclein

Barbara Elena Stopschinski, Brandon B. Holmes, Gregory M. Miller…·Marc I. Diamond

The paper identifies specific glycosaminoglycan (GAG) structural requirements for the uptake of Tau, Aβ, and α-synuclein aggregates by cells.

180 citationstop 1%

humanexperimental assay

𝕏 PostBluesky

NeuroscienceScientific ReportsPeer-reviewedApr 17, 2018

Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs)

Jennifer N. Rauch, John Jing-Wei Chen, Alexander W. Sorum…·Kenneth S. Kosik

The paper identifies 6-O-sulfation on heparan sulfate proteoglycans as critical for tau internalization and shows it regulates uptake in multiple cell models.

211 citationstop 1%

𝕏 PostBluesky