Deletion of Crtc1 leads to hippocampal neuroenergetic impairments associated with depressive-like behavior
Antoine Cherix, Carole Poitry‐Yamate, Bernard Lanz, Olivia Zanoletti, Jocelyn Grosse, Carmen Sandi, Rolf Gruetter A, Jean‐René Cardinaux
This study shows that deleting Crtc1 in mice causes hippocampal metabolic impairments linked to depressive-like behavior and identifies ebselen as a potential treatment.
Molecular Psychiatry · Oct 12, 2022Peer-reviewedNeuroscience