Carmen Sandi

The paper maps the lipidomic architecture of the adult mouse brain at micrometric scale, revealing spatial lipid organization and its functional relevance.

The paper shows low testosterone increases anxiety by altering astrocytic mitochondrial structure and function at the nucleus accumbens blood-brain barrier in rats.

The paper identifies neurometabolic predictors of mental effort in the frontal cortex using 1H-MRS and machine learning.

The paper investigates how lactate levels in the dmPFC/dACC relate to motivation for physical effort and neural activity, finding a systemic influence of lactate on brain metabolism.

This study identifies specific prelimbic cortex cell types and their connectivity patterns involved in cooperative learning in rats.

This study shows that adolescent stress disrupts ventral hippocampus redox balance and mitochondrial function, leading to behavioral and neural abnormalities linked to schizophrenia.

This study shows that reduced glucocorticoid responsiveness to stress causes multiple PTSD-related traits in rats, including fear extinction deficits, small hippocampal volume, and REMS disturbances.

This study shows that Mfn2 in NAc D2-MSNs regulates social dominance and neuronal function, while D1-MSNs show transient effects on competitiveness.

This study shows that higher glutathione levels in the nucleus accumbens predict better sustained performance in reward-incentivized effort tasks and that manipulating GSH levels affects motivation.

This study shows that deleting Crtc1 in mice causes hippocampal metabolic impairments linked to depressive-like behavior and identifies ebselen as a potential treatment.

A mouse model with impaired mitochondrial pyruvate import shows neuronal hyperexcitability and seizures despite reduced oxidative phosphorylation.

The paper examines mitochondrial respiratory chain capacity and its association with stress-related behaviors in mice, identifying brain networks linked to anxiety-like behavior.

This study examines how acute stress affects peripersonal space representation by measuring visuotactile interactions and cortisol levels in humans.

This study shows that peripubertal stress slows adult spatial learning and is linked to corticosterone response adaptation, not peak levels, and affects emotional reactivity and hippocampal plasticity.

This study shows that early α-synuclein pathology in a mouse model does not cause mitochondrial respiration deficits in the striatum and amygdala, even under corticosterone-induced hyperactivity.

This study investigates the metabolic effects of acetyl-L-carnitine in the nucleus accumbens of stressed mice, showing normalization of energy-related metabolites in dominant mice.

This study shows that glucocorticoid receptor (GR) in the nucleus accumbens and dopaminoceptive neurons influences social dominance in rodents.

This study links neurochemical profiles in the nucleus accumbens to individual differences in anxiety traits and situational stress using 7T 1H-MRS in healthy males.

This study shows that chronic corticosterone worsens alpha-synuclein pathology and neurodegeneration in a mouse model of Parkinson's disease.