Author

Ting Yin

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2 Bioengineering· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 4 Organism:human· 4 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Assay:CRISPR screen· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

Penney M. GilbertiD· 3 shared Aaron H. RosensteiniD· 2 shared Danielle SerraiD· 2 shared Maria H. T. NguyeniD· 2 shared Michael GartoniD· 2 shared Nitya GulatiiD· 2 shared Peter W. ZandstraiD· 2 shared Rasha Al-attariD· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersSynthetic Biology

Penney M. GilbertORCID

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Author profile →

5 papers

Recent·Most cited

FAST-STEM: A human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices

Aaron H. Rosenstein, Rangarajan Sambathkumar, Brandon M. Murareanu, Navroop K. Dhaliwal, Fumao Sun, Xinyaun Zhao, Abolfazl Dadvar, Rasha Al-attar, Andrew Chai, Nitya Gulati, Ting Yin, Maria Nguyen, Danielle Serra, Tania Devina, Aanshi Gandhi, , Michael Garton

FAST-STEM accelerates human pluripotent stem cell engineering by enabling rapid transgene integration and differentiation into multiple cell types.

bioRxiv · May 23, 2024 · PreprintBioengineering

A Flexible Transgene Integration Landing-Pad Toolkit in Human Induced Pluripotent Stem Cells Enables Facile Cellular Engineering, Gene Zygosity Control, and Parallel Transgene Integration

Aaron H. Rosenstein, Maria H. T. Nguyen, Rasha Al-attar, Danielle Serra, Nitya Gulati, Ting Yin, Penney M. Gilbert, Michael Garton

This paper introduces a toolkit for transgene integration in hiPSCs using a safe-harbour locus, enabling controlled transgene configurations and efficient cellular engineering.

bioRxiv · Mar 3, 2023 · PreprintSynthetic Biology

Discrete-to-analog signal conversion in human pluripotent stem cells

Laura Prochazka, Yale S. Michaels, Charles Lau, M. Mona Siu, Ting Yin, Diana Wu, Esther Jang, Ross D. Jones, Mercedes Vázquez‐Cantú, Penney M. Gilbert, Himanshu Kaul, Yaakov Benenson, Peter W. Zandstra

The paper develops synthetic gene circuits in human pluripotent stem cells that convert discrete cell states into analog signals by integrating miRNAs with miSFITs for controlled effector protein production.

bioRxiv · Nov 5, 2021 · PreprintSynthetic Biology

Nicotinamide promotes differentiation of pancreatic endocrine progenitors from human pluripotent stem cells through poly (ADP-ribose) polymerase inhibition

Curtis M. Woodford, Ting Yin, Huntley H. Chang, Romario Regeenes, Ravi Nagaraj Vellanki, Haneesha Mohan, Bradly G. Wouters, Jonathan V. Rocheleau, Michael B. Wheeler, Peter W. Zandstra

This paper shows nicotinamide promotes pancreatic endocrine progenitor differentiation via PARP inhibition, increasing Nkx6.1 and NAD+/NADH ratio.

bioRxiv · Apr 21, 2020 · PreprintDevelopmental Biology

Synchronous nonmonotonic changes in functional connectivity and white matter integrity in a rat model of sporadic Alzheimer's disease

Catarina Tristão‐Pereira, Yujian Diao, Ting Yin, Analina R. da Silva, Bernard Lanz, Katarzyna Pierzchała, Carole Poitry‐Yamate, Ileana Jelescu

This study shows nonmonotonic changes in brain connectivity and white matter in a rat Alzheimer's model, suggesting a compensatory mechanism that could be a therapeutic target.

bioRxiv · Jan 30, 2020 · PreprintNeuroscience