Author

Charlie Chaluma Luchen

Centre for Infectious Disease Research in ZambiaORCID 0000-0002-3093-4635Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Bertha T. Nzangwa· 1 shared Bruno SovraniD· 1 shared Caroline Cleopatra ChisengaiD· 1 shared Daniel R. MendeiD· 1 shared Dhvani H. KuntawalaiD· 1 shared Gonçalo J. PiedadeiD· 1 shared Jongchan KimiD· 1 shared Josephine F. Frempong· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Bertha T. Nzangwa

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1 paper

Recent·Most cited

Microbiota-derived indole metabolites inhibit rotavirus infection in vitro and in vivo and in human infants

Nurul I. Wirusanti, Yannick van Schajik, Jongchan Kim, Josephine F. Frempong, Nagina Simkhada, Sydney Fisher, Nicholas Pucci, Gonçalo J. Piedade, Charlie Chaluma Luchen, Mwelwa Chibuye, Michelo Simuyandi, Caroline Cleopatra Chisenga, Suwilanji Silwamba, Kennedy Chibesa, Bertha T. Nzangwa, , Vanessa Harris

This study shows microbiota-derived indole metabolites inhibit rotavirus infection in human infants and animal models through the AhR pathway.

bioRxiv · Oct 29, 2025 · PreprintMicrobiology