Author

Armando D. Mendez

Texas Biomedical Research InstituteORCID 0000-0002-3096-8472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:non-human primate· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Colin B. RorexiD· 3 shared Diako EbrahimiiD· 3 shared Jake D. LehleiD· 3 shared Rachael Springman-RodrigueziD· 3 shared Elizabeth SommeriD· 2 shared Mohadeseh Soleimanpour-MoghadamiD· 2 shared Niloofar HaghjooiD· 2 shared Ayub BokaniiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersBiochemistry

Colin B. RorexORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 28, 2026

CODMA-A3: A Competitive Oligo-based DNA Modification Assay Applied to APOBEC Enzymes

Colin B. Rorex, Rachael Springman-Rodriguez, Armando D. Mendez…·Diako Ebrahimi

CODMA-A3 is a high-throughput assay for screening APOBEC3 variants, detecting substrate competition and activity changes without protein purification.

DOI 10.64898/2026.10.27.760525

humanDNA methylation

Cancer BiologybioRxivPreprintSep 30, 2026

Deciphering the Network Architecture of APOBEC3-Driven Mutagenesis in HPV-Positive Head and Neck Cancers

Jake D. Lehle, Mohadeseh Soleimanpour-Moghadam, Niloofar Haghjoo…·Diako Ebrahimi

The paper identifies APOBEC3A and APOBEC3B mutagenic effects in HPV-positive HNSCC by analyzing single-cell data, showing distinct mutational signatures linked to tumor stages and vaccine targets.

DOI 10.64898/2026.09.17.752415

humanscRNA-seq

GenomicsbioRxivPreprintAug 12, 2026

APOBEC3G Splicing Defects in Nonhuman Primate Models Result in Disparate Viral Mutational Profiles Relative to Humans

Armando D. Mendez, Rachael Springman-Rodriguez, Ayub Bokani…·Diako Ebrahimi

This study identifies APOBEC3G splicing defects in nonhuman primates that lead to different viral mutation profiles compared to humans.

DOI 10.64898/2026.08.06.743345

non-human primatestatistical model