Deciphering the Network Architecture of APOBEC3-Driven Mutagenesis in HPV-Positive Head and Neck Cancers
Jake D. Lehle, Mohadeseh Soleimanpour-Moghadam, Niloofar Haghjoo…·Diako Ebrahimi
The paper identifies APOBEC3A and APOBEC3B mutagenic effects in HPV-positive HNSCC by analyzing single-cell data, showing distinct mutational signatures linked to tumor stages and vaccine targets.