Author

Tiffany V. Roach

Drexel UniversityORCID 0000-0002-3098-3314Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Kari F. LenhartiD· 2 shared Akanksha BhatnagariD· 1 shared Bhanu Chandra KarisettyiD· 1 shared Ellen M. ArmouriD· 1 shared Erika A BachiD· 1 shared Felice ElefantiD· 1 shared Haolin ZhangiD· 1 shared Mariah BeaveriD· 1 shared

Activity by Year

2020-2024 · peak 2/yr

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10 top collaborators · 24 mutual co-author links

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2 shared papersDevelopmental Biology

Kari F. LenhartORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintNov 3, 2024

Conversion of somatic sex identity in the testis induces female-specific cellular behaviors in the soma and early oocyte specification in the germline

Tiffany V. Roach, Sneh Harsh, Rajiv Sainath…·Kari F. Lenhart

This study shows that loss of chinmo in Drosophila testis causes somatic cells to adopt female-specific behaviors and influence germline sex identity, leading to early oocyte specification.

1 citation

Drosophilaexperimental assay

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Developmental BiologyDevelopmentPeer-reviewedJun 1, 2024

Mating-induced ecdysone in the testis disrupts soma-germline contacts and stem cell cytokinesis

Tiffany V. Roach, Kari F. Lenhart

The paper shows that mating in Drosophila males increases ecdysone signaling, disrupting germline stem cell cytokinesis and causing stem cell loss over time.

11 citations

Drosophilaexperimental assay

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NeuroscienceMolecular and Cellular NeurosciencePeer-reviewedNov 5, 2020

Tip60 protects against amyloid-β peptide-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegenerative progression

Haolin Zhang, Bhanu Chandra Karisetty, Akanksha Bhatnagar…·Felice Elefant

This study shows Tip60 protects against Aβ42-induced transcriptomic changes in different ways during early and late stages of AD progression in Drosophila.

16 citations

Drosophilabulk RNA-seq

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