Author

Enoch Antwi

University of FreiburgORCID 0000-0002-3100-646XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Synthetic Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Abdulmajeed SalamahiD· 1 shared Ada L. OlinsiD· 1 shared Barbara Di VenturaiD· 1 shared Benedikt BrorsiD· 1 shared Bo ZhuiD· 1 shared Chu-Yen Chen· 1 shared Donald E. OlinsiD· 1 shared Hang YiniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperSynthetic Biology

Abdulmajeed SalamahORCID

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3 papers

Recent·Most cited

TREND: A generalizable synthetic enhancer discovery platform for targeted immunotherapy

Yingbo Jia, Chu-Yen Chen, Bo Zhu, Zhigui Wu, Yi‐Chia Wu, Ren‐Qi Wang, Abdulmajeed Salamah, Sushmita Halder, Yen‐Nien Liu, Yingjie Guo, Ying Chen, Luca Scimeca, Hang Yin, Tejas Sabu, Yutao Wang, , Ming-Ru Wu

TREND identifies context-specific enhancers for targeted immunotherapy by analyzing TF-responsive enhancer libraries in ovarian cancer.

bioRxiv · May 7, 2026 · PreprintSynthetic Biology

Requirements for mammalian promoters to decode transcription factor dynamics

Enoch Antwi, Yassine Marrakchi, Özgün Çiçek, Thomas Brox, Barbara Di Ventura

The paper investigates how mammalian promoters decode transcription factor dynamics using optogenetics, deep learning, and mathematical modeling, finding that inefficient coupling between TF binding and transcription initiation enhances decoding.

Nucleic Acids Research · Apr 18, 2023Peer-reviewedSystems Biology

Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4

Enoch Antwi, Ada L. Olins, Vladimir B. Teif, Matthias Bieg, Tobias Bauer, Zuguang Gu, Benedikt Brors, Roland Eils, Donald E. Olins, Naveed Ishaque

The paper maps DNA methylation changes during differentiation of HL-60/S4 cells, showing enhancer and CTCF site methylation drives transcriptional reprogramming.

Biology Open · Jan 1, 2020Peer-reviewedGenomics