Author

Matthias Bieg

German Cancer Research CenterORCID 0000-0002-3606-4917Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Roland EilsiD· 2 shared Zuguang GuiD· 2 shared Ada L. OlinsiD· 1 shared Adam A. AbeshouseiD· 1 shared Adrian Ally· 1 shared Adrian Baez‐OrtegaiD· 1 shared Andreas BehreniD· 1 shared Andrew BerchuckiD· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Roland EilsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

Lauri A. Aaltonen, Federico Abascal, Adam A. Abeshouse, Hiroyuki Aburatani, David J. Adams, Nishant Agrawal, Keun Soo Ahn, Sung-Min Ahn, Hiroshi Aikata, Rehan Akbani, Kadir Caner Akdemir, Hikmat A Al‐Ahmadie, Sultan T. Al‐Sedairy, Fátima Al‐Shahrour, Malik Alawi, , Johann Sebastian De Bono

This study identifies germline genetic variants influencing somatic mutation patterns in 2,642 cancer genomes across 39 cancer types.

Nature · Feb 5, 2020Peer-reviewedGenomics

Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4

Enoch Antwi, Ada L. Olins, Vladimir B. Teif, Matthias Bieg, Tobias Bauer, Zuguang Gu, Benedikt Brors, Roland Eils, Donald E. Olins, Naveed Ishaque

The paper maps DNA methylation changes during differentiation of HL-60/S4 cells, showing enhancer and CTCF site methylation drives transcriptional reprogramming.

Biology Open · Jan 1, 2020Peer-reviewedGenomics

Impact of cancer mutational signatures on transcription factor motifs in the human genome

Calvin Wing Yiu Chan, Zuguang Gu, Matthias Bieg, Roland Eils, Carl Herrmann

The paper links cancer mutational signatures to changes in transcription factor binding site motifs, showing correlations between motif alteration and signature information content.

BMC Medical Genomics · May 20, 2019Peer-reviewedBioinformatics