Vladimir B. Teif

This study shows that CTCF binding is influenced by the epigenetic state of the N-terminal nucleosome and its orientation relative to CTCF motifs, affecting chromatin architecture.

This study compares genomic alterations and transcriptional phenotypes in circulating tumor DNA and matched metastatic tumors in SCLC patients, finding cfDNA reflects tumor mutations, identifies resistance mechanisms, and tracks tumor evolution.

This study identifies patient-specific and common nucleosome repositioning patterns in breast cancer tissues and links them to cancer pathways and liquid biopsy applications.

This study identifies changes in nucleosome positioning and packing in chronic lymphocytic leukaemia, linking them to epigenetic mechanisms and patient stratification.

The paper develops a computational method to predict cell-type-specific nucleosome-binding abilities of transcription factors using ChIP-seq, MNase-seq, and DNase-seq data, identifying new potential pioneer transcription factors.

The paper develops a chromatin hierarchical lattice framework to predict heterochromatin nanodomains and identifies DNA sequence and protein binding factors that determine their formation and boundaries.

NucPosDB curates nucleosome positioning data and cfDNA datasets for gene regulation and diagnostics, enabling analysis of nucleosome occupancy and computational model training.

The paper maps DNA methylation changes during differentiation of HL-60/S4 cells, showing enhancer and CTCF site methylation drives transcriptional reprogramming.

The paper investigates how CTCF binding influences chromatin boundaries through asymmetric nucleosome arrays and NRL changes in mouse cells.

The paper investigates how PARylation of CTCF affects its chromatin binding and gene expression in breast cells during cell cycle arrest.