Author

James W. Askew

University of Nebraska Medical CenterORCID 0000-0002-3110-8976Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Benjamin Jacob DrapkiniD· 1 shared Chaitra RaoiD· 1 shared Deepan ChatterjeeiD· 1 shared Dianna H. HuismaniD· 1 shared Heidi M. VieiraiD· 1 shared Kurt W. FisheriD· 1 shared Robert A. SvobodaiD· 1 shared Robert E. LewisiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Benjamin Jacob DrapkinORCID

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1 paper

Recent·Most cited

KSR1 mediates small-cell lung carcinoma tumor initiation and cisplatin resistance

Deepan Chatterjee, Robert A. Svoboda, Dianna H. Huisman, Benjamin Jacob Drapkin, Heidi M. Vieira, Chaitra Rao, James W. Askew, Kurt W. Fisher, Robert E. Lewis

This study identifies KSR1 as a critical regulator of SCLC tumor initiation and cisplatin resistance, showing that its disruption enhances cisplatin toxicity and reduces tumor-initiating cells.

Molecular Cancer Research · Feb 10, 2025Peer-reviewedCancer Biology