Mengyi Cao

This study investigates how environmental factors like temperature, pheromones, and symbiotic bacteria influence the formation of infective juveniles in Steinernema hermaphroditum.

This paper develops a genetic part library for constructing tunable dsRNA circuits in C. elegans to enable precise RNA interference.

This study identifies a novel mechanism by which E. coli Nissle 1917 colonizes the nematode Steinernema hermaphroditum through immune cell interactions and cuticle persistence.

This paper establishes a CRISPR-Cas9 system in Steinernema hermaphroditum for targeted gene knockout and mutant line generation, demonstrating its utility for studying nematode biology and symbiosis.

This study adapts CRISPR-Cas9 gene editing to the dioecious Steinernema feltiae, generating stable mutants and demonstrating X-linked inheritance and phenotypic changes.

This paper identifies genes in Xenorhabdus griffiniae that change expression in response to the presence of its nematode host Steinernema hermaphroditum, with ymdA affecting host colonization.

This study identifies two subspecies of Xenorhabdus griffiniae and shows that prophages drive intraspecies genomic variation.

This paper develops a CRISPR-Cas9 genome-editing protocol for Steinernema entomopathogenic nematodes, enabling targeted mutagenesis and phenotypic analysis in two species.

The paper identifies Steinernema hermaphroditum CS34 as a self-fertilizing hermaphrodite with genetic tractability for studying symbiosis and parasitism.