John Hardy

This study uses an event-based model to analyze cognitive decline in adults with Down syndrome, showing similar patterns to Alzheimer's disease and identifying useful measures for tracking decline stages.

This study identifies genetic overlaps between frontotemporal dementia and immune-mediated diseases, finding strong enrichment with rheumatoid arthritis and moderate enrichment with other immune conditions.

This paper develops and validates a polygenic hazard score to predict age-specific Alzheimer's disease risk using genetic data from multiple cohorts.

The paper uses GWAS summary statistics to identify enrichment of heritability in immune system annotations for Alzheimer’s and Parkinson’s diseases.