Author
Washington University in St. LouisORCID 0000-0001-9665-5922Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Benjamin Grodner, David T. S. Wu, Sumin Hahm…·Iwijn De Vlaminck
The paper examines spatial bacterial arrangement in oral biofilms from healthy and diseased implants, finding that disease is associated with single-genus patches and proposing spatial structure as a biomarker for microbiome stability.
Iris Broce, Chin Hong Tan, Chun Chieh Fan…·Rahul S. Desikan
The paper identifies genetic variants associated with Alzheimer's disease and cardiovascular risk factors, showing lipid-related enrichment and pleiotropy beyond APOE.
Luke W. Bonham, Celeste M M. Karch, Chun Chieh Fan…·Murray Grossman
The paper identifies a genetic variant near CXCR4 associated with increased risk for PSP and PD, showing dysregulation of CXCR4 and microglia-related genes in neurodegenerative diseases.
Iris Broce, Celeste M M. Karch, Natalie Wen…·John Collinge
This study identifies genetic overlaps between frontotemporal dementia and immune-mediated diseases, finding strong enrichment with rheumatoid arthritis and moderate enrichment with other immune conditions.
John Budde, Rita J. Martinez, Simon Hsu…·Celeste M M. Karch
The paper develops a precise CRISPR/Cas9 genome-editing platform for human iPSCs, demonstrating improved editing efficiency and minimal off-target effects.