Molecular BiologybioRxivPreprint
Novel Transgenic Humanized Alpha-1 Antitrypsin Deficiency Mouse Model on Murine SERPINA1 Null Background
Regina A. Oshins, Alek M. Aranyos, Skylar Grey…·Nazli Khodayari
This paper develops a humanized transgenic mouse model for AATD with a SERPINA1-null background, showing liver disease features and supporting its use for studying the disease and drug discovery.
DOI 10.1101/2024.10.11.617858