Author

Mark Brantly

University of Florida HealthORCID 0000-0003-0189-1565Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Nazli KhodayariiD· 3 shared Regina A. OshinsiD· 3 shared Huiping ZhouiD· 2 shared Alek M. AranyosiD· 1 shared Borna MehradiD· 1 shared Brittney PooleiD· 1 shared Derrick Zhao· 1 shared Ishan J. PateliD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Nazli KhodayariORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 11, 2024

Novel Transgenic Humanized Alpha-1 Antitrypsin Deficiency Mouse Model on Murine SERPINA1 Null Background

Regina A. Oshins, Alek M. Aranyos, Skylar Grey…·Nazli Khodayari

This paper develops a humanized transgenic mouse model for AATD with a SERPINA1-null background, showing liver disease features and supporting its use for studying the disease and drug discovery.

DOI 10.1101/2024.10.11.617858

mousebulk RNA-seq

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Cell BiologybioRxivPreprintAug 20, 2024

Extracellular Vesicle-Associated Neutrophil Elastase Activates Hepatic Stellate Cells and Promotes Liver Fibrogenesis via ERK1/2 Pathway

Regina A. Oshins, Zachary Greenberg, Yunling Tai…·Nazli Khodayari

5 citations

mouseexperimental assay

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Molecular BiologybioRxivPreprintAug 31, 2023

Profiling plasma extracellular vesicle-derived microRNAs for noninvasive diagnosis of alpha-1 antitrypsin deficiency associated liver disease

Regina A. Oshins, Zhiguang Huo, Brittney Poole…·Nazli Khodayari

This study identifies miRNA biomarkers in plasma extracellular vesicles for noninvasive detection of AATD liver disease, achieving an AUC of 0.751 with a four-miRNA model.

DOI 10.1101/2023.08.31.555751

humanbulk RNA-seq

𝕏 PostBluesky