Author

Dolores Fernández‐Ortuño

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-3134-3095Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:fungi (other)· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:plant (other)· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Alejandro Pérez‐GarcíaiD· 1 shared Álvaro PolonioiD· 1 shared Andrea Tobian Herreno· 1 shared David ScheuringiD· 1 shared Frederik SommeriD· 1 shared Lucía Jiménez CastroiD· 1 shared Luoyu wu· 1 shared Marat Magomedov· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioinformatics

Alejandro Pérez‐GarcíaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Multi-knockout of 29 phytotoxic proteins and metabolites does not completely abolish virulence of the necrotrophic fungus Botrytis cinerea

Nassim Safari, Patrick Pattar, Marat Magomedov, Andrea Tobian Herreno, Shekhar Chule, Dolores Fernández‐Ortuño, Luoyu wu, Frederik Sommer, David Scheuring, Michael Schroda, Remco Stam, Matthias Hahn

Deleting 27 CDIP-candidate genes (26 confirmed CDIPs) and two phytotoxin biosynthesis genes in Botrytis cinerea nearly abolishes apple infection but leaves slow leaf lesions, pointing to redundant, unidentified host-killing factors.

bioRxiv · Aug 27, 2026 · PreprintMolecular Biology✦ In-depth digest

Explainable AI for end-to-end pathogen target discovery and molecular design

Lucía Jiménez Castro, Dolores Fernández‐Ortuño, Alejandro Pérez‐García, Álvaro Polonio

APEX identifies pathogen targets and designs inhibitors using explainable AI, highlighting key residues and guiding molecular design.

bioRxiv · May 15, 2026 · PreprintBioinformatics