Jean Popovici

The paper identifies and characterizes two novel Plasmodium vivax merozoite proteins, PvMP45 and PvMP36, which bind reticulocyte receptors and are targets of protective antibodies, suggesting their potential as vaccine candidates.

This study identifies MaRNAV-1 as an intracellular virus in Plasmodium vivax that increases transmission and alters host immune responses.

This study shows that short-term ex vivo culture of Plasmodium vivax enriches late asexual stages and selectively filters clones without inducing major transcriptional changes.

The paper identifies 283 immunogenic Plasmodium vivax proteins using a high-density peptide array, revealing potential vaccine targets and serological markers for vivax malaria.

The paper identifies a conserved complex formed by PTRAMP, CSS, and Ripr in Plasmodium species that facilitates merozoite invasion of erythrocytes and shows its structural and functional conservation across species.

This paper develops a cost-effective MinION sequencing assay to detect G6PD deficiency SNPs in malaria-endemic regions, showing high reliability and concordance with Sanger sequencing.

The paper investigates copy number variations of Plasmodium vivax genes in Duffy-positive and Duffy-negative Ethiopians, finding higher duplication rates in Duffy-positive samples.

The paper isolates a human monoclonal antibody that targets Plasmodium vivax AMA1, blocking both pre-erythrocytic and blood stage infections.

The paper analyzes genetic diversity in PvDBP and PvEBP from P. vivax isolates in Cambodia and Madagascar, finding higher PvEBP copy numbers in Madagascar and evidence of diversifying selection on PvEBP.