Author

Kian Soon Hoon

Charles Darwin UniversityORCID 0000-0002-2310-3403Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 3 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Sarah AuburniD· 4 shared Hidayat TrimarsantoiD· 3 shared Anisah Jantim· 2 shared Bridget E. BarberiD· 2 shared Giri Shan RajahramiD· 2 shared Jacob A. F. WestawayiD· 2 shared Kim A. PieraiD· 2 shared Matthew J. GriggiD· 2 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Sarah AuburnORCID

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4 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 19, 2026

Pfcrt copy number amplification detected in a Plasmodium falciparum outbreak

Anjana Rai, Chiyun Lee, Hidayat Trimarsanto…·Sarah Auburn

The paper identifies pfcrt copy number amplification as a new antimalarial resistance mechanism in Plasmodium falciparum and develops a TaqMan assay for its detection.

DOI 10.64898/2026.06.18.732750

whole-genome sequencingexperimental assay

GenomicsbioRxivPreprintMar 23, 2026

Integrative genomics of Plasmodium knowlesi reveals parasite-intrinsic regulators of severe human malaria

Jacob A. F. Westaway, Ernest Diez Benavente, Michal Kucharski…·Matthew J. Grigg

This study identifies parasite-intrinsic transcriptional programs associated with severe P. knowlesi malaria through integrative GWAS, transcriptomic, and eQTL analyses of clinical isolates.

DOI 10.64898/2026.03.22.713451

virusbulk RNA-seq

MicrobiologyScientific ReportsPeer-reviewedDec 21, 2025

Rapid detection of G6PD deficiency SNPs using a novel amplicon-based MinION Sequencing Assay

Costanza Tacoli, Mariana Kleinecke, Kian Soon Hoon…·Jean Popovici

This paper develops a cost-effective MinION sequencing assay to detect G6PD deficiency SNPs in malaria-endemic regions, showing high reliability and concordance with Sanger sequencing.

1 citation

humanlong-read sequencing

BioinformaticsbioRxivPreprintJul 27, 2022

MinSNPs: an R package for derivation of resolution-optimised SNP sets from microbial genomic data

Kian Soon Hoon, Deborah C. Holt, Sarah Auburn…·Philip M. Giffard

MinSNPs is an R package that derives resolution-optimised SNP sets from microbial genomic data for surveillance and genetic analysis.

DOI 10.1101/2022.07.27.501805

humanmouse