Lauren Tereshko

A Poisson-multinomial model for quantifying gene therapy vector integrity using quadplex digital PCR

This paper introduces a Poisson-multinomial model for quantifying gene therapy vector integrity using quadplex digital PCR, enabling accurate analysis of sequence integrity and genetic linkage across four targets.

A novel method for quantitation of AAV genome integrity and residual DNAs using duplex digital PCR

This paper introduces a novel model to improve the accuracy and quantifiable range of duplex ddPCR assays for assessing AAV genome integrity.

Ciliary neuropeptidergic signaling dynamically regulates excitatory synapses in postnatal neocortical pyramidal neurons

This study shows that ciliary neuropeptidergic signaling dynamically modulates excitatory synapses in postnatal neocortical pyramidal neurons, with SSTR3 playing a key role.