Piali Sengupta

The paper shows that cilia in C. elegans form stereotyped interciliary contacts independent of physical proximity, suggesting instructive mechanisms guide these interactions.

TRAP-seq of C. elegans AFD neurons reveals three temperature-duration expression modules; CREB-driven RCAN-1 acts in parallel with MEF-2 to repress premature expression of a delayed gene, ins-39.

This study shows that sensory neuron cilia in adult C. elegans can regenerate after injury, involving both cell-intrinsic and glial pathways distinct from developmental ciliogenesis.

The paper identifies a glial attachment mechanism in C. elegans neurons that affects cilia morphology and function.

The paper shows temperature experience modulates transcription and trafficking of thermoreceptors in C. elegans AFD neurons to regulate response plasticity.

The paper shows that asymmetric molecular mechanisms in C. elegans AWC neurons drive symmetric odor response plasticity, revealing how lateralized signaling enhances behavioral flexibility.

This study identifies a variant ionotropic receptor in C. elegans enteric neurons that detects ingested salts and regulates salt stress resistance.

This study investigates how cilia structure and intraflagellar transport (IFT) differentially modulate chemosensory responses in C. elegans neurons.

The paper identifies feedforward and feedback mechanisms in C. elegans AFD neurons that mediate rapid thermosensory response adaptation through cGMP and calcium signaling.

The paper identifies how temperature stimuli are encoded in the gene expression of C. elegans thermosensory neurons, revealing transcriptional dynamics that drive plasticity.

This study shows C. elegans uses temperature-sensing neurons to preemptively activate defenses against hydrogen peroxide, which becomes more reactive at higher temperatures.

This study shows that developmental dauer arrest in C. elegans alters chemoreceptor expression, leading to changes in olfactory behavior and attraction to food-related odorants.

This study identifies CREB as a key regulator of dauer formation in C. elegans by directly controlling TGF-β expression in ASI neurons.

This study shows that ciliary neuropeptidergic signaling dynamically modulates excitatory synapses in postnatal neocortical pyramidal neurons, with SSTR3 playing a key role.

This study identifies GRDN-1 as a regulator of dendrite extension and cilium positioning in C. elegans sensory neurons, showing distinct regulatory mechanisms in AQR and PQR neurons.

The paper shows that feeding state modulates a sensory circuit in C. elegans to alter thermotaxis behavior through gut-brain signaling.

This study shows that enteric bacteria produce tyramine, which modulates host sensory behavior and food choice in C. elegans by mimicking host neurotransmitters.

The paper introduces a GFP-based cGMP sensor, WincG2, for real-time imaging of cGMP dynamics in intact C. elegans, showing its sensitivity to cGMP changes and responses to NaCl and SDS.

This paper shows that TORC2 in C. elegans gut communicates feeding state to the brain, regulating developmental decisions and foraging behaviors through hormonal signaling.