Coronavirus spherules are supported by a novel triple-layer protein lattice
Patrick Morley Phillips, Joanna Wells, Naveen Mathew, Nicole Doyle, Sarah Keep, Parijat Majumder, James Boris Gilchrist, Philippa C. Hawes, Jonathan M. Grimes, Maria Harkiolaki, Daniel K. Clare, Helena Jane Maier
This study identifies a triple-layer protein lattice within coronavirus spherules and confirms a molecular pore in DMVs, providing insights into coronavirus replication structures.
bioRxiv · Oct 9, 2026 · PreprintMicrobiology