Author

Helena Jane Maier

The Pirbright InstituteORCID 0000-0002-2901-5578Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

Nicole DoyleiD· 2 shared Andrew E. FirthiD· 1 shared Ben F. LuisiiD· 1 shared Daniel K. ClareiD· 1 shared Felix RandowiD· 1 shared James Boris GilchristiD· 1 shared Joanna WellsiD· 1 shared Jonathan M. GrimesiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Nicole DoyleORCID

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2 papers

Recent·Most cited

Coronavirus spherules are supported by a novel triple-layer protein lattice

Patrick Morley Phillips, Joanna Wells, Naveen Mathew, Nicole Doyle, Sarah Keep, Parijat Majumder, James Boris Gilchrist, Philippa C. Hawes, Jonathan M. Grimes, Maria Harkiolaki, Daniel K. Clare, Helena Jane Maier

This study identifies a triple-layer protein lattice within coronavirus spherules and confirms a molecular pore in DMVs, providing insights into coronavirus replication structures.

bioRxiv · Oct 9, 2026 · PreprintMicrobiology

The stem loop 2 motif is a site of vulnerability for SARS-CoV-2

Valeria Lulla, Michal P. Wandel, Katarzyna Justyna Bandyra, Rachel Ulferts, Mary Wu, Tom Dendooven, Xiaofei Yang, Nicole Doyle, Stephanie Oerum, Rupert C. L. Beale, Sara M. O’Rourke, Felix Randow, Helena Jane Maier, William Scott, Yiliang Ding, , Ben F. Luisi

The paper identifies the stem loop 2 motif as a vulnerable site in SARS-CoV-2 that can be targeted by antisense oligonucleotides to inhibit replication and infection.

Journal of Virology · May 6, 2021Peer-reviewedMolecular Biology